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Xenogen IVIS 200 Imager The Xenogen IVIS 200 Biophotonic Imager excels at imaging light emitted from small animals such as mice or rats but can also be used to image light emitted from Western blots, culture dishes and 96-well plates. The IVIS 200 can quantitate bioluminescent or chemiluminescent signals produced by luciferases and other reporters, as well as fluorescent signals produced by fluorescent proteins (GFP, RFP, etc.) and other fluorescent molecules. The instrument has the capability of imaging light in 2-D or pseudo 3-D mode. The IVIS 200 is connected to a gas anesthesia unit that allows continuous administration of isofluorane gas for anesthetizing animals during imaging. Imaging times vary from 1 sec to 10 min depending on signal strength. Up to five animals can be imaged simultaneously. Analysis of imaging data is carried out on a separate computer that is available to users. Analysis software can be purchased from Xenogen Corporation to allow analysis by users on their own computers. IVIS 200 Imager | brochure | training guide | applications
Xenogen IVIS 3D Imager The IVIS 3D Imaging System offers rotational axis imaging of bioluminescent and fluorescent light sources within living animal models. With a unique optomechanical design, the IVIS 3D provides eight imaging views about the longitudinal axis of the animal without physically rotating the animal or the CCD camera. A 3D diffuse tomography version of Living Image software analyzes bioluminescent images to provide the in vivo source brightness, location, and size. The spatial resolution of the reconstruction is 1–3 mm, depending on source location. IVIS 3D Imager | brochure | website | applications
Leica Stereo Fluorescence Microscope The Leica MZ-FLIII Microscope is used for visualizing fluorescent proteins and other fluorescent molecules in mice and other small animals in 3-D.  The microscope is equipped with a QImaging cooled CCD Camera with Near IR capability. Filters for a wide range of fluorescent materials are available. Leica MZ-FLIII Microscope | brochure | user manual | applications Mauna Kea Cellvizio Fiber Optic Imaging System Cellvizio is a micron resolution optical imaging system that enables researchers to observe and quantify physiological phenomena at the cellular and sub-cellular levels in live laboratory animals. It provides an powerful alternative to intravital imaging using conventional microscopy. Cellvizio Imaging System | brochure | website | applications Tissue/Cell Culture Room A tissue/cell culture room is available for sterile procedures and for culturing tissues and cells obtained from animals. Culture room equipment includes a biohazard hood, CO2 incubators, and an inverted phase contrast microscope.
		Leica  MZ-FLIII Microscope
		Cellvizio Imaging System
Technical Services A full range of technical services are available to allow facility users to take full advantage of in vivo imaging technology in their research. Services include: Animal handling/husbandry IP, IV  arterial, and orthotopic administration of cells and other agents Dissection and organ removal Other (inquire)
Animal Models Available to Facility Users 4T1 Syngeneic Breast Cancer Xenograft Model MDA-MB-231 Human Breast Cancer Xenograft Model MCF-7 Human Breast Cancer Xenograft Model A wide range of additional models are available from Caliper/Xenogen Corporation