Tufts/TMC Small Animal Imaging/Preclinical Testing Facility

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Xenogen IVIS 200 Biophotonic








      Imaging System

4T1 Breast Cancer








      Model

The Tufts University/Tufts Medical Center Small Animal Imaging Facility provides equipment and expertise for imaging bioluminescence and fluorescence and preclinical testing of therapeutics, in live animals. Major instrumentation includes a state-of-the-art Xenogen IVIS 200 Biophotonic Imager, a VisualSonics Vevo 2100 Ultrasound Imaging system and a Leica MZ-FLIII Stereo Fluorescence Microscope. The technology provided by these instruments is applicable to a wide range of research areas that include tumor and stem cell biology, infectious disease, neurobiology, wound healing and signal transduction. The facility is also equipped to develop imagable animal models and perform surgical procedures and cell/tissue culture to support in vivo imaging and preclinical testing studies with these instruments.

For cancer researchers at academic institutions and companies, the facility offers novel luciferase- and fluorescent protein-based syngeneic and zenograft models as well as technical services for studying in vivo tumor growth and metastasis and preclinical drug testing. A technician is available for animal handling/husbandry, introduction of tumor cells and therapeutics into animals, and other services. Use the links above for further information about in vivo imaging applications, to view instrument and service fees, and to schedule instrument and technician time.